Nanoparticle Tracking Analysis (NTA) utilizes the properties of both light scattering and Brownian motion in order to obtain the nanoparticle size distribution of samples in liquid suspension.

Particles in liquid suspension are loaded into a sample chamber, which is illuminated by a specially shaped laser beam. Particles in the path of the beam scatter the laser light which is easily collected by the 20x microscope objective and is viewed with a digital camera.? The camera captures a video of the particles moving under Brownian motion. The Nanoparticle Tracking Analysis (NTA) software analyses many particles individually and simultaneously (particle-by-particle), and by using the Stokes Einstein equation, calculates their hydrodynamic diameters. NanoSight instruments provide high resolution nanoparticle size, count-based concentration and aggregation measurements while a fluorescence mode provides specific results for suitably labelled particles.? With real time monitoring, subtle changes in the characteristics of particle populations are provided with all of these analyses confirmed by visual validation.

NTA_laser_block

The technique uses low sample volumes with little sample preparation which, along with minimal instrument consumables, reduces running costs on a day to day basis.? The technique is also non-destructive and the sample can be recovered if required.

NanoSight NTA systems support work within ISO19430: 2016 Particle Tracking Analysis (PTA) Method and ASTM E2834-12 (2012) Standard Guide for Measurement of Particle Size Distribution of Nanomaterials in Suspension by Nanoparticle Tracking Analysis (NTA).

Applications include:

  • Exosomes, microvesicles and extracellular vesicles characterization.
  • Viral vaccine research and development.
  • Development of drug delivery systems.
  • Protein aggregation studies.
  • Nanotoxicology.

NanoSight LM10

NanoSight LM10

Доступная цена и универсальная конструкция со сменными лазерами.

Подробнее
Измерение Particle concentration, Размер частиц (гранулометрический состав), Агрегация белков
Диапазон размеров частиц *10nm - 1000nm
Технология Анализ траекторий наночастиц

NanoSight NS300

NanoSight NS300

Оптимизация для флуоресценции.

Подробнее
Измерение Particle concentration, Размер частиц (гранулометрический состав), Агрегация белков
Диапазон размеров частиц *10nm - 1000nm
Технология Анализ траекторий наночастиц

NanoSight LM10

NanoSight LM10

Доступная цена и универсальная конструкция со сменными лазерами.

NanoSight NS300

NanoSight NS300

Оптимизация для флуоресценции.

Подробнее Подробнее
Измерение Particle concentration, Размер частиц (гранулометрический состав), Агрегация белков Particle concentration, Размер частиц (гранулометрический состав), Агрегация белков
Диапазон размеров частиц *10nm - 1000nm *10nm - 1000nm
Технология Анализ траекторий наночастиц Анализ траекторий наночастиц

NanoSight LM10

NanoSight NS300

NanoSight LM10 NanoSight NS300

Доступная цена и универсальная конструкция со сменными лазерами.

Оптимизация для флуоресценции.

Подробнее Подробнее
Технология
Анализ траекторий наночастиц
Анализируемые свойства
Particle concentration
Размер частиц (гранулометрический состав)
Диапазон размеров частиц *10nm - 1000nm *10nm - 1000nm

*Sample and instrument configuration dependent

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